Search results for "large [Cosmology]"

showing 10 items of 272 documents

Large solutions for nonlinear parabolic equations without absorption terms

2012

In this paper we give a suitable notion of entropy solution of parabolic $p-$laplacian type equations with $1\leq p<2$ which blows up at the boundary of the domain. We prove existence and uniqueness of this type of solutions when the initial data is locally integrable (for $1<p<2$) or integrable (for $p=1$; i.e the Total Variation Flow case).

Entropy solutionsIntegrable systemMathematical analysisp-LaplacianMathematics::Analysis of PDEsGeodetic datumNonlinear parabolic equationsMathematics - Analysis of PDEsentropy solutions; large solutions; p-laplacian; total variation flowp-LaplacianFOS: MathematicsLarge solutionsUniquenessTotal variation flowEntropy (arrow of time)AnalysisMathematicsAnalysis of PDEs (math.AP)Journal of Functional Analysis
researchProduct

Oligomerization and hemolytic properties of the C-terminal domain of pyolysin, a cholesterol-dependent cytolysin

2013

Pyolysin (PLO) belongs to the homologous family of the cholesterol- dependent cytolysins (CDCs), which bind to cell membranes containing cholesterol to form oligomeric pores of large size. The CDC monomer structure consists of 4 domains. Among these, the C-terminal domain 4 has been implicated in membrane binding of the monomer, while the subsequent processes of oligomerization and membrane insertion have primarily been assigned to other domains of the molecule. Recombinantly expressed or proteolytic fragments that span domain 4 of the CDCs streptolysin O and perfringolysin O bind to membranes but fail to oligomerize, and they inhibit the activity of the respective wild-type toxins. We repo…

ErythrocytesMembrane bindingCellprotein bindingBiochemistryoligomerHemolysin Proteinschemistry.chemical_compoundReaction kineticsToxic materialsMonomersprotein domainRecombinant ProteinsHemolysisunclassified drugcytolysinmedicine.anatomical_structureMembraneBiochemistryStreptolysinsStreptolysinLarge sizeBacterial ToxinsBiologyCholesterol-dependent cytolysinHemolysisoligomerizationMembrane LipidsBacterial ProteinsProteolytic fragmentsEscherichia colimedicineAnimalsMonomer structuresMolecular BiologySheep Domesticcarboxy terminal sequenceC-terminal domainsCholesterolC-terminusCell MembraneHemolytic activitycholesterolCell Biologymedicine.diseaseProtein Structure TertiaryCell membranesKineticschemistryOligomersProtein MultimerizationPyolysinprotein pyolysinMembrane insertionCytology
researchProduct

The reaction structure of the LEDA research centre: Development and design

2017

In the last twenty years, the field of earthquake engineering experienced a noticeable improvement. The results of experimental and theoretical researches have contributed to the development of modern technical codes, which provide innovative solutions for the structural assessment and new design approaches. Despite this large amount of improvements, several open questions are still open, and the need for large scale testing has been deeply proved and discussed. A new research facility, namely the Laboratory of Earthquake engineering and Dynamic Analysis (LEDA), has been recently completed at the University of Enna "Kore". This research centre, funded with a grant from Italian Ministry of E…

ExperimentalEarthquake engineeringLarge scale testingPseudo-dynamic testingBuilding and ConstructionSafety Risk Reliability and QualityGeotechnical Engineering and Engineering Geology
researchProduct

Innovation Initiatives in Large Software Companies : A Systematic Mapping Study

2018

Context: To keep the competitive advantage and adapt to changes in the market and technology, companies need to innovate in an organised, purposeful and systematic manner. However, due to their size and complexity, large companies tend to focus on the structure in maintaining their business, which can potentially lower their agility to innovate.Objective:The aims of this study are to provide an overview of the current research on innovation initiatives and to identify the challenges of implementing those initiatives in the context of large software companies.Method: The investigation was primarily performed using a systematic mapping approach of published literature on corporate innovation …

FOS: Computer and information sciencesKnowledge managementCorporate innovationinnovation initiatives02 engineering and technologyentrepreneurshipCorporate innovationinnovationsComputer Science - Software EngineeringSoftwareohjelmistoala0502 economics and business0202 electrical engineering electronic engineering information engineeringLarge software companiescorporatesInnovationtietotekniikkayrityksetta113business.industry05 social sciencessystematic mapping study050301 education020207 software engineeringsoftware companiesyrittäjyysComputer Science ApplicationsinnovaatiotSoftware Engineering (cs.SE)Innovation initiativeCorporate entrepreneurshipSystematic mappingbusiness0503 educationSoftware050203 business & managementInformation Systems
researchProduct

Lean Internal Startups for Software Product Innovation in Large Companies: Enablers and Inhibitors

2018

Context: Startups are disrupting traditional markets and replacing well-established actors with their innovative products.To compete in this age of disruption, large and established companies cannot rely on traditional ways of advancement, which focus on cost efficiency, lead time reduction and quality improvement. Corporate management is now looking for possibilities to innovate like startups. Along with it, the awareness and the use of the Lean startup approach have grown rapidly amongst the software startup community and large companies in recent years. Objective: The aim of this study is to investigate how Lean internal startup facilitates software product innovation in large companies.…

FOS: Computer and information sciencesProcess managementQuality managementlarge companiesProcess (engineering)lean startupmethod-in-actionContext (language use)02 engineering and technologyComputer Science - Computers and SocietyComputer Science - Software EngineeringohjelmistoalaComputers and Society (cs.CY)0502 economics and business0202 electrical engineering electronic engineering information engineeringProduct (category theory)lean internal startupsuuryrityksetta113software product innovationProduct innovationinternal startup05 social sciences020207 software engineeringlean-ajatteluinnovaatiotSoftware Engineering (cs.SE)Conceptual frameworkHardware and ArchitectureBusinessLean startup050203 business & managementSoftwareLead timeInformation Systems
researchProduct

Carbon Monoxide in the Cold Debris of Supernova 1987A

2013

We report spectroscopic and imaging observations of rotational transitions of cold CO and SiO in the ejecta of SN1987A, the first such emission detected in a supernova remnant. In addition to line luminosities for the CO J=1-0, 2-1, 6-5, and 7-6 transitions, we present upper limits for all other transitions up to J=13-12, collectively measured from the Atacama Large Millimeter Array (ALMA), the Atacama Pathfinder EXperiment (APEX), and the Herschel Spectral and Photometric Imaging REceiver (SPIRE). Simple models show the lines are emitted from at least 0.01 solar masses of CO at a temperature &gt; 14 K, confined within at most 35% of a spherical volume expanding at ~ 2000 km/s. Moreover, we…

FOS: Physical sciencesAstrophysicsWAVELENGTHindividual (SN1987A) [supernovae]FACILITYEjectaSupernova remnantSolar and Stellar Astrophysics (astro-ph.SR)3-DIMENSIONAL STRUCTURELine (formation)PhysicsSolar massSN-1987AINSTRUMENTsupernova remnants [ISM]Astronomy and AstrophysicsAtacama Large Millimeter ArrayDebrisSupernovaSpireEJECTACASSIOPEIAPhysics and AstronomyAstrophysics - Solar and Stellar Astrophysics13. Climate actionSpace and Planetary ScienceREMNANTSN 1987A
researchProduct

Metal-organic magnets with large coercivity and ordering temperatures up to 242°C.

2020

International audience; Magnets derived from inorganic materials (e.g., oxides, rare-earth–based, and intermetallic compounds) are key components of modern technological applications. Despite considerable success in a broad range of applications, these inorganic magnets suffer several drawbacks, including energetically expensive fabrication, limited availability of certain constituent elements, high density, and poor scope for chemical tunability. A promising design strategy for next-generation magnets relies on the versatile coordination chemistry of abundant metal ions and inexpensive organic ligands. Following this approach, we report the general, simple, and efficient synthesis of light…

FabricationMaterials sciencemagneettiset ominaisuudetPyrazineMetal ions in aqueous solutionmagneetitIntermetallicNanotechnology02 engineering and technologyorganometalliyhdisteet010402 general chemistrylarge coercivity7. Clean energy01 natural sciencesordering temperaturesCoordination complexchemistry.chemical_compoundMoleculechemistry.chemical_classificationMultidisciplinarymetal-organic magnets[CHIM.MATE]Chemical Sciences/Material chemistrykompleksiyhdisteetCoercivity021001 nanoscience & nanotechnologykiteet0104 chemical scienceschemistryMagnetlämpötila0210 nano-technologyScience (New York, N.Y.)
researchProduct

Hierarchical-ACA DBEM for anisotropic three-dimensional time-domain fracture mechanics

2012

Fast BEMLarge scale computationsSettore ING-IND/04 - Costruzioni E Strutture AerospazialiAnisotropic elastodynamics fracture mechanic
researchProduct

Hierarchical fast BEM for anisotropic time-harmonic 3-D elastodynamics

2012

The paper presents a fast boundary element method for anisotropic time-harmonic 3-D elastodynamic problems. The approach uses the hierarchical matrices format and the ACA algorithm for the collocation matrix setup and a preconditioned GMRES solver for the solution. The development of this approach for the anisotropic case presents peculiar aspects which deserve investigation and are studied in the paper leading to the employed computational strategy and its effective tuning. Numerical experiments are presented to assess the method accuracy, performances and numerical complexity. The method ensures adequate accuracy allowing remarkable reductions in computation time and memory storage.

Fast BEMMathematical optimizationCollocationTime harmonicMechanical EngineeringComputationSolverLarge scale computationsGeneralized minimal residual methodComputer Science ApplicationsMatrix (mathematics)Modeling and SimulationGeneral Materials ScienceAnisotropyAnisotropic elastodynamicAlgorithmBoundary element methodCivil and Structural EngineeringMathematics
researchProduct

On the hidden side of liquidity

2012

This paper deals with the informativeness of iceberg orders, also known as hidden limit orders (HLOs). Namely, we analyze how the market reacts when the presence of hidden volume in the limit order book is revealed by the trading process. We use high frequency book and transaction data from the Spanish Stock Exchange, including a large sample of executed HLOs. We show that just when hidden volume is detected, traders on the opposite side of the market become more aggressive, exploiting the opportunity to consume more than expected at the best quotes. However, neither illiquidity nor volatility increases in the short-term. Furthermore, the detection of hidden volume has no relevant price imp…

Financial economicsEconomics Econometrics and Finance (miscellaneous)Volume (computing)Large sampleMarket liquidityTerm (time)Order (exchange)Stock exchangeEconometricsEconomicsLimit (mathematics)Volatility (finance)Transaction dataRelevant informationThe European Journal of Finance
researchProduct